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Análise transcriptómica das glândulas salivares de Anopheles stephensi

Análise transcriptómica das glândulas salivares de Anopheles stephensi

Ana Domingos / Joana Manuel Couto / Renato Silva

68,10 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2026
Materia
Biologia, ciencias de la vida
ISBN:
9786209559433
68,10 €
IVA incluido
Disponible
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A malária tem um grande impacto na saúde social e, por essa razão, as interações entre o parasita da malária e o mosquito vetor podem ser elucidadas por diferentes métodos, incluindo a transcriptómica. O RNA-seq é uma nova abordagem que, através da comparação do transcriptoma de um organismo em diferentes condições, pode fornecer um catálogo de genes diferencialmente expressos, constituindo uma informação crucial para a seleção de alvos potenciais para vacinas candidatas contra a malária. Confirmado por qPCR e montado com ensaios de silenciamento por knockdown, o eventual papel relevante desses genes na infecção pode ser compreendido, levando à exploração de novos alvos para o desenvolvimento de vacinas que bloqueiam a transmissão.

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