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Neutralisation de l’hyperacidité gastrique par les antiacides minéraux

Neutralisation de l’hyperacidité gastrique par les antiacides minéraux

Abdelali Merah / Leila Mekahlia / Youcef Hadef

105,30 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2025
Materia
Farmacología
ISBN:
9786209252631
105,30 €
IVA incluido
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L’hyperacidité gastrique, due à une production excessive d’acide chlorhydrique, peut provoquer brûlures d’estomac, dyspepsie et reflux gastro-œsophagien. Les antiacides minéraux, tels que l’hydroxyde d’aluminium, l’hydroxyde de magnésium et le carbonate de calcium, neutralisent cet excès d’acide et soulagent les symptômes. Cette étude a évalué la capacité de neutralisation acide (ANC) de 13 antiacides commercialisés en Algérie, en utilisant le titrage pH-métrique et la méthode titrimétrique. Les résultats montrent que la plupart des produits dépassent les normes FDA, avec Rennie (carbonate de calcium et magnésium) en tête, suivi de Maalox. La forme galénique influence l’efficacité, les liquides surpassant les comprimés à croquer. Bien que certains produits à base d’alginate et de bicarbonate présentent une ANC plus faible, leur mécanisme protecteur demeure pertinent. La teneur en sodium doit également être considérée. Ces données offrent un guide pour le choix thérapeutique et l’orientation des recherches futures.

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